October 26, 2010
Does Tylenol® Cause Asthma?
There have been a number of recent comments about the possible correlation between Tylenol® (acetaminophen) and asthma. An article in the American Journal of Respiratory Critical Care Medicine found the risk to be about 2.5 times greater in teenagers using acetaminophen at least monthly. The findings come from a study of 323,000 13- and 14-year-olds from 50 nations.
The real questions are these: Is acetaminophen dangerous? Does use by pregnant women increase the development of asthma in children? Is intake once a month or once a year dangerous to teenagers?
These questions are more theoretical than real. There is not a great deal of evidence in the literature. And, a correlation does not necessarily indicate a cause. It may very well be that children and pregnant women at risk of asthma might be more likely to take acetaminophen.
The lead author, Dr. Richard W. Beasley, stresses that the study does not show a direct cause, but says that further studies must be done to see if there is such a connection.
The American College of Allergy, Asthma & Immunology (ACAAI) has issued the following statement: “We understand your concerns and are aware of the news that suggests a link between acetaminophen and asthma. It is not definitive, and we will follow this issue carefully. For now, we recommend you use the asthma medications as prescribed and acetaminophen only when needed.”
From an allergist’s standpoint, I agree with this advice.
